The Importance of Particle Size Analysis in Preformulation Studies
![Image](https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEjQojYhqh1oSH6cQPtdOt0rcwhOUWqz2F6NyPNzaPUmg3Dk0cUZZ4-yt3sgPGRXflEHb7LwkZcfAo7FYsyXBTcaapDxeOgYO06Af32pqo4XWkz-Fzr8Dm5Wnkxvc-J-SuDDecRsQHAh8xOBIM6SS2Y61q3ew0CaFkuQ2dtJ3niN8RErTh4BY_CEh0ZfWg/w640-h362/Particle-Size-Analysis.jpg)
The size of the particles is called particle size. The particle size of the API is closely related to the homogeneity of the preparation process in terms of mixing, the accuracy of dosage, and compressibility, and it has an impact on the solubility, duration of action, site of action, stability, and safety of the drug formulation. And the particle size control of drugs has an important influence on drug effectiveness, strength, and security. Therefore, particle size is an essential object of study in preformulation studies for innovative medicines. Preformulation research is a vital link in drug development, directly affecting the subsequent development process and final application of drugs. Preformulation research aims to determine the pros and cons of potential drug molecules at the initial research stage and to screen candidates for drug molecules, involving the synthesis of new drug molecules, biological activity screening, pharmacokinetics, toxicology, safety evaluation, etc