Medical News

 Saponins are one of the main active ingredients of many herbal medicines such as ginseng, Polygala tenuifolia, Platycodon grandiflorum, licorice, rhizoma anemarrhenae, and radix bupleurum. Pharmacological studies have shown that saponins have biological activities such as antibacterial, antitumor, modulation of body metabolism and immunity, and treatment of cardiovascular diseases and diabetes mellitus. The in vivo metabolites of saponins were analyzed by chromatography-mass spectrometry to provide favorable evidence for the elucidation of the therapeutic mechanism of Chinese medicine. Liquid chromatography-mass spectrometry (LC/MS) is a bioanalytical technique that combines the high separation performance of high-performance liquid chromatography HPLC with the high sensitivity and specificity of tandem mass spectrometry. It does not require complete chromatographic separation between analytes, and its multi-window detection capability allows the quantitative analysis of multiple...

 We all know that there are many causes of hair loss, but we never thought that the culprit of hair loss is intestinal flora. Scientists have pointed out that the analysis of the metabolites of the gut microflora is essential to understand how they affect human health, and that these metabolites can regulate the function of the immune system and the central nervous system. Metabolite analysis refers to the study of small molecules (metabolites) in biological systems, including cells, tissues, and organisms. It aims to identify, quantify, and understand the metabolic pathways, changes in metabolite levels, and relationships between metabolites and biological processes. Techniques used for metabolite analysis include NMR spectroscopy, mass spectrometry, and HPLC. The goal is to gain insights into biological function and identify markers for disease diagnosis and treatment. Gut microbes have a potential impact on human health, such as the corresponding changes in the gut microflora fo...