What's the role of Mini-pig animal models in drug development?
The development of various human diseases is highly complex. For drug developers to study human pathogenesis and pathological changes and observe and evaluate the efficacy of drugs, it is necessary to construct models that mimic human diseases, such as organoid or animal models, to explore the nature of human diseases and evaluate the effectiveness of new drugs. In vitro, ex vivo, or rodent models are generally used in the early stage of drug discovery . As new drug candidates progress from discovery to preclinical development and scale-up drug preparation, large animal models such as Minipigs, dogs, and monkeys are gradually adopted. The porcine model is one of the large animal models used in many laboratories and drug research sites. The size and characteristics of pigs vary by species. Minipigs were first used in medical research in Europe before being introduced to the United States in the 1980s. Minipigs are a commonly used animal model for pharmaceutical research. Minipigs a...