An anti-influenza virus compound, Gibberellin B
Isatis Radix, also known as the big blue heel, is the dried root of the plant woad or big blue-green, which can be used clinically for influenza, mumps, chickenpox, and measles. The liver is the leading site of drug metabolism , and applying the liver microsomal model allows for metabolite analysis studies of drugs. Drug metabolite analysis has evolved rapidly to become an essential part of pharmacokinetic studies . According to a study reported on the internet, it was found that based on the systematic screening of the active antiviral ingredients of radix isatidis, straight heliotropin B was the most abundant compound among the 31 compounds isolated from the aqueous extract of radix isatidis, and compound activity testing studies showed that it had significant antiviral and antioxidant activities. Therefore, the lignan compound Gibberellin B contained in Isatidis Radix no toginseng is one of the critical active substance bases of Isatidis Radix no toginseng against viruses...