What are the Differences between in vivo and in vitro testing of drugs for toxicology Studies?
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In toxicology studies, there are two main types of tests used to assess the safety and potential toxic effects of drugs: in vivo tests and in vitro tests. We know that the traditional method of drug toxicology research is to use animal models for in vivo drug testing. Although this method can fully reflect the various toxic effects of drugs and allow long-term observation of chronic toxic effects, there are many interfering factors and it is difficult to conduct metabolic and mechanistic studies. With the development of science and technology, the use of free organs, cultured cells, or organelles for toxicological in vitro testing has slowly emerged. Toxicology is the science of studying the harmful effects of chemical, physical, biological, and other exogenous factors on biological systems. It can study the toxic reactions of chemical substances on living organisms, their severity, frequency of occurrence, and mechanisms of toxic effects, as well as qualitative and quantitative ev